PRECISION POLYMER

Custom Services

Tell us your target molecular structure, degree of polymerization, and required quantity to get started with custom synthesis.

  1. 1Submit Request
  2. 2Assessment
  3. 3Synthesis
  4. 4Quality Control
  5. 5Delivery

1. Monofunctional Precision PEG

Customization Scope
mPEG–OH, mPEG–NH₂, mPEG–COOH, mPEG–SH, mPEG–NHS, mPEG–Mal, mPEG–N₃, etc.
Key Parameters
Degree of polymerization (DP) of the precision PEG, terminal functional group, form of the reactive moiety, purity, and order quantity
Typical Applications
Drug modification, bioconjugation, protein modification, surface functionalization of nanomaterials
Lead Time
We estimate lead time based on the target structure, purity requirements, order quantity, and raw material availability. The final lead time will be confirmed after technical review and stated in the quotation.
Information to Provide
Target structure, precision PEG DP, functional groups, purity, quantity

2. Bifunctional Precision PEG

Customization Scope
Homobifunctional or heterobifunctional precision PEG derivatives such as HO–PEG–OH, NH₂–PEG–NH₂, COOH–PEG–COOH, NH₂–PEG–COOH and Mal–PEG–NHS
Key Parameters
Precision PEG DP, combination of functional groups at both ends, protected or activated end-group forms, purity and quantity
Typical Applications
Bioconjugation at both ends, drug linkers, protein conjugation, hydrogel crosslinking, and surface modification
Lead Time
We estimate lead time based on the target structure, purity requirements, order quantity, and raw material availability. The final lead time will be confirmed after technical review and stated in the quotation.
Information to Provide
Target structure, precision PEG DP, functional group types at both ends, purity, quantity

3. Multifunctional Precision PEG

Customization Scope
Y-shaped two-arm, three-arm, four-arm and other multi-arm precision PEG derivatives; different terminal functional groups can be designed on request
Key Parameters
Branching core, number of arms, precision PEG DP of each arm, combination of terminal functional groups, purity and quantity
Typical Applications
Multivalent bioconjugation, drug carriers, hydrogel crosslinking, multi-site surface functionalization of nanomaterials
Lead Time
We estimate lead time based on the target structure, purity requirements, order quantity, and raw material availability. The final lead time will be confirmed after technical review and stated in the quotation.
Information to Provide
Target branched structure, number of arms, chain length of each arm, functional group types, purity, quantity

4. Precision PEG Lipids & Excipients

Customization Scope
Precision PEG–DSPE, PEG–DMG, PEG–DMA, PEG–DSG, PEG–cholesterol and other PEG lipid derivatives
Key Parameters
Precision PEG DP, lipid anchor, hydrophobic tail length and structure, terminal group, purity and quantity; chiral configuration considered where needed
Typical Applications
LNP-based delivery of mRNA and other nucleic acids, liposomes, nanomedicine, drug formulation, and excipient development
Lead Time
We estimate lead time based on the target structure, purity requirements, order quantity, and raw material availability. The final lead time will be confirmed after technical review and stated in the quotation.
Information to Provide
Target PEG lipid structure, PEG DP, tail and linker groups, purity, quantity and application requirements

5. Precision PEG Block Copolymers

Customization Scope
Precision PEG-b-PLA, precision PEG-b-PLGA, precision PEG-b-PCL, precision PEG-b-PTMC and other copolymers containing a precision PEG block
Key Parameters
DP of the precision PEG block, composition and target molecular weight of the second block, block ratio, end-group structure, dispersity and quantity
Typical Applications
Polymeric micelles, degradable nanocarriers, controlled-release materials, biomedical self-assembling materials
Lead Time
We estimate lead time based on the target structure, purity requirements, order quantity, and raw material availability. The final lead time will be confirmed after technical review and stated in the quotation.
Information to Provide
Target block structure, precision PEG chain length, composition and molecular weight of the other blocks, dispersity requirements, quantity

6. Other Precision Polymers

Customization Scope
Precision polyethers, precision polyesters, polyglycerols and other polymers with specific chain length, end-group, composition or structural requirements
Key Parameters
Monomer and repeat-unit structure, target DP, molecular weight and its distribution, end-group structure, composition or sequence requirements, purity and quantity
Typical Applications
Biomedical materials, pharmaceutical excipients, high-performance resins, functional materials and high-end electronic chemicals
Lead Time
We estimate lead time based on the target structure, purity requirements, order quantity, and raw material availability. The final lead time will be confirmed after technical review and stated in the quotation.
Information to Provide
Target structure or monomer type, DP and molecular weight requirements, end groups, performance specifications, purity, quantity

7. Fluorescent Dyes

Customization Scope
Fluorescein, rhodamine, cyanine dyes (Cy series), BODIPY, Nile Blue, other classes of organic dyes, and their functionalized or precision-PEGylated derivatives
Key Parameters
Dye scaffold, excitation and emission wavelengths, reactive functional group, spacer or precision PEG chain length, water solubility, purity and quantity
Typical Applications
Fluorescent labeling, cell and tissue imaging, molecular probes, nanomedicine tracking and bioanalysis
Lead Time
We estimate lead time based on the target structure, purity requirements, order quantity, and raw material availability. The final lead time will be confirmed after technical review and stated in the quotation.
Information to Provide
Target dye structure or spectral requirements, conjugation group, solubility requirements, purity and quantity

8. Click Chemistry Reagents

Customization Scope
Reagents bearing click-reactive groups such as azides, terminal alkynes, DBCO, BCN, TCO, and tetrazines, as well as bifunctional precision PEG linkers
Key Parameters
Click reaction type, combination of reactive groups, precision PEG chain length or spacer length, choice of protecting group, purity, and order quantity
Typical Applications
Bioorthogonal conjugation, protein and nucleic acid modification, drug conjugation, surface functionalization of nanocarriers and materials
Lead Time
We estimate lead time based on the target structure, purity requirements, order quantity, and raw material availability. The final lead time will be confirmed after technical review and stated in the quotation.
Information to Provide
Target linker structure, reactive groups, PEG DP or spacer length, purity, quantity

9. Precision PEG ADC Linkers

Customization Scope
Antibody–drug conjugate (ADC) linkers with precision PEG spacers, including options with terminal maleimides or cleavable motifs such as Val–Cit–PAB and Val–Ala–PAB. Other linker designs are also available on request.
Key Parameters
Precision PEG DP, antibody-conjugation end group, linker cleavage mechanism, drug attachment site, protecting groups, purity and quantity
Typical Applications
ADC development, conjugation for targeted drug delivery, and optimization of linker hydrophilicity and spatial configuration
Lead Time
We estimate lead time based on the target structure, purity requirements, order quantity, and raw material availability. The final lead time will be confirmed after technical review and stated in the quotation.
Information to Provide
Target linker structure, precision PEG DP, conjugation end group, cleavage mode, drug attachment requirements, purity and quantity

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