News and Insights

News and Case Studies

2026-11-11

Case Study

How a Problematic Bottle of PEG-Amine Led to Precision PEG

Professor Shiyong Liu recounts how questions about commercial PEG-Amine samples led his team to investigate end-group impurities and storage stability, develop high-fidelity end-functionalization using carbamate linkages, and pursue single-molecular-weight precision PEG.

2026-10-26

Case Study

Precision PEG: The Next Core Driver of Innovative Drug Development That CXO Companies Should Not Overlook

Advances in peptides, antibody–drug conjugates (ADCs), and nucleic acid therapeutics are bringing linkers and delivery materials into drug design at an earlier stage. For CXO companies providing contract research (CRO) and contract development and manufacturing (CDMO) services, the ability to connect material structure, quality, and application performance is becoming an important part of project development.

2026-10-23

Case Study

Medical Applications of PEG: Long-Acting Modification, Precision Linkers, and Nanodelivery

Polyethylene glycol (PEG) is a hydrophilic polymer widely used in medicine. Its high water solubility, flexible chain structure, and diverse options for end-group modification make PEG and its derivatives useful as pharmaceutical excipients, for modifying drug molecules, and for constructing delivery carriers. Applications span small-molecule drugs, protein and peptide therapeutics, antibody–drug conjugates, and nucleic acid therapeutics. Selecting appropriate chain lengths, end groups, and linkages can modulate drug solubility, stability, behavior in vivo, and release.