Y-(mPEG)2-Mal

Y-shaped bis(methoxy-poly(ethylene glycol)) with a single maleimide conjugation handle (Y-(mPEG)2-MAL) is a Y-shaped branched precision PEG derivative. It contains two methoxy-capped PEG arms and a single maleimide conjugation terminus. Discrete chain lengths with different degrees of polymerization are available. The maleimide can add to cysteine thiols or other thiolated modules, providing a handle for conjugation at thiol sites. The two hydrophilic arms attach to a target site through a single functional terminus, allowing arm length, branched topology, and reactive-end chemistry to be studied as separate variables in molecular modification.

Customization available.