Y-(mPEG)2-NHS Ester

Y-shaped bis(methoxy-poly(ethylene glycol)) with a single N-hydroxysuccinimide ester conjugation handle (Y-(mPEG)2-NHS) is a Y-shaped branched precision PEG derivative. It contains two methoxy-capped PEG arms and a single N-hydroxysuccinimide ester conjugation terminus. Discrete chain lengths with different degrees of polymerization are available. The NHS ester can form amide bonds with primary amines, enabling conjugation to amine-containing small molecules, peptides, proteins, or material surfaces. The two hydrophilic arms attach to a target site through a single functional terminus, allowing arm length, branched topology, and reactive-end chemistry to be studied as separate variables in molecular modification.

Customization available.