Molecular Precision Defines MaterialsPrecision Materials Shape the Future
Our Four Core Areas Are Single-Molecular-Weight Precision Polyethylene Glycol (PEG) and Its Derivatives, Precision PEG Lipids, Polyether and Polyester Pharmaceutical Excipients, and High-Performance Precision Polymers. We Develop and Manufacture These Materials for Industrial Applications.
We are developing precision polymers with well-defined molecular composition, chain length, sequence, and structure to make material performance easier to control and predict. Conventional polymers, by comparison, are typically characterized by average molecular weight, dispersity, and average composition.
Repeat Unit (n)
CH3–(OCH2CH2)24–OH
One Bead = –OCH2CH2– Repeating Unit
Degree of Polymerization (n)
24
Molecular Formula
C49H100O25
Example: mPEG-OH(PPT-101 Series)
Defined Chain Length, Single Molecular Weight
Degree of Polymerization (n)
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Conventional Polydisperse PEGPrecision PEG
Products
Browse by category →product group →series → catalog number. Each series lists catalog numbers by degree of polymerization. Select a pack size, add it to your inquiry list, and submit the list when ready.
Methoxy Poly(ethylene glycol) Alcohol; Poly(ethylene glycol) Monomethyl Ether (mPEG-OH) is a precision PEG derivative with a defined chain length. One end bears a methoxy group. The other end bears a hydroxyl group. Discrete chain lengths with different degrees of polymerization are available. The terminal hydroxyl group can be further modified by esterification, etherification, or other functional-group transformations, enabling the synthesis of functional PEG derivatives and precision molecular linkers. Applications: Precision PEG derivatization; Bioconjugation linker synthesis; Drug modification and functional-molecule conjugation. Customization available.
Methoxy Poly(ethylene glycol) Alcohol; Poly(ethylene glycol) Monomethyl Ether (mPEG-OH) is a precision PEG derivative with a defined chain length. One end bears a methoxy group. The other end bears a hydroxyl group. Discrete chain lengths with different degrees of polymerization are available. The terminal hydroxyl group can be further modified by esterification, etherification, or other functional-group transformations, enabling the synthesis of functional PEG derivatives and precision molecular linkers. Applications: Precision PEG derivatization; Bioconjugation linker synthesis; Drug modification and functional-molecule conjugation. Customization available.
Methoxy-poly(ethyleneglycol)-maleimide(mPEG-MAL) is a monofunctional precision PEG derivative with a defined chain length. One end bears a methoxy group. The other end bears a maleimide group. Discrete chain lengths with different degrees of polymerization are available. The maleimide can add to cysteine thiols or other thiolated modules, providing a handle for conjugation at thiol sites. Capping one end defines the direction of derivatization, enabling the hydrophilic PEG segment to be attached to a target molecule and functional linkers of the required length to be constructed. Applications: Cysteine-site modification; Thiol-selective bioconjugation; Protein–functional material conjugation. Customization available.
Hydroxyl-terminated PEG arm on a cyclic poly(ethylene glycol) scaffold (cPEG-PEG-OH) is a cyclic-topology derivative bearing a pendant PEG arm. The specified conjugation or functional groups are located on the pendant segment. Discrete chain lengths with different degrees of polymerization are available. The terminal hydroxyl group can be further modified by esterification, etherification, or other functional-group transformations. The cyclic scaffold retains its topological features, while the pendant arm provides conjugation and presentation functions. This allows the effects of ring structure and pendant-chain length on molecular conjugation to be distinguished. Applications: Cyclic topology effect studies; Molecular conjugation through pendant arms; Precision PEG derivatization; Bioconjugation linker synthesis. Customization available.
Alpha-(amino)-omega-(carboxy)poly(ethylene glycol) (H2N-PEG-COOH) is a heterobifunctional precision PEG derivative with a defined chain length. The two ends bear primary amine and carboxyl groups, respectively. Discrete chain lengths with different degrees of polymerization are available. The primary amine can react with activated carboxyl groups or NHS esters to form amide bonds and introduce carboxyl-containing functional moieties. The carboxyl group can be activated for amide coupling with primary-amine-containing molecules, retaining a handle for subsequent ligand or carrier attachment. The two end groups can be coupled sequentially using compatible reactions and appropriate protection strategies, enabling surface immobilization, functional-molecule bridging, and directional spacer synthesis. Applications: Amide-based bioconjugation; Peptide and functional small-molecule conjugation; Amino-PEG derivatization; Amine-containing molecule conjugation; Drug and ligand modification; Carboxyl linker synthesis. Customization available.
Alpha,omega-dihydroxyPoly(ethylene glycol); Discrete Poly(ethylene glycol) Diol (HO-PEG-OH) is a homobifunctional precision PEG derivative with a defined chain length. Both ends bear hydroxyl groups. Discrete chain lengths with different degrees of polymerization are available. The terminal hydroxyl group can be further modified by esterification, etherification, or other functional-group transformations. Identical reactive sites at both ends support molecular bridging or derivatization on both sides. The conjugation scheme can be designed around the number of target sites. Applications: Precision PEG derivatization; Bioconjugation linker synthesis; Drug modification and functional-molecule conjugation. Customization available.
Alpha-(amino)-omega-(carboxy)poly(ethylene glycol) (H2N-PEG-COOH) is a heterobifunctional precision PEG derivative with a defined chain length. The two ends bear primary amine and carboxyl groups, respectively. Discrete chain lengths with different degrees of polymerization are available. The primary amine can react with activated carboxyl groups or NHS esters to form amide bonds and introduce carboxyl-containing functional moieties. The carboxyl group can be activated for amide coupling with primary-amine-containing molecules, retaining a handle for subsequent ligand or carrier attachment. The two end groups can be coupled sequentially using compatible reactions and appropriate protection strategies, enabling surface immobilization, functional-molecule bridging, and directional spacer synthesis. Applications: Amide-based bioconjugation; Peptide and functional small-molecule conjugation; Amino-PEG derivatization; Amine-containing molecule conjugation; Drug and ligand modification; Carboxyl linker synthesis. Customization available.
Alpha,omega-bis(p-toluenesulfonate)poly(ethylene glycol) (TsO-PEG-OTs) is a homobifunctional precision PEG derivative with a defined chain length. Both ends bear tosylate groups. Discrete chain lengths with different degrees of polymerization are available. The tosylate acts as a leaving group, enabling nitrogen- or sulfur-containing functional moieties to be introduced by nucleophilic substitution. Identical reactive sites at both ends support molecular bridging or derivatization on both sides. The conjugation scheme can be designed around the number of target sites. Applications: PEG end-group conversion; Nucleophilic substitution intermediates; Linker extension. Customization available.
4-Armhydroxyl-functionalized discrete poly(ethylene glycol) (4-Arm-PEG-OH) is a 4-arm precision PEG derivative. The PEG arms present terminal hydroxyl groups. Discrete chain lengths with different degrees of polymerization are available. The terminal hydroxyl group can be further modified by esterification, etherification, or other functional-group transformations. The multiarm structure provides attachment sites for multivalent ligand display or network construction. Arm number, chain length, and functional-group equivalents can be varied to compare crosslink spacing and molecular presentation. In this series, n denotes the number of ethylene glycol repeat units in each PEG arm. Applications: Four-arm PEG multivalent conjugation; Branched PEG construction; Crosslinking and site-density studies; Precision PEG derivatization; Bioconjugation linker synthesis. Customization available.
Y-shapedbis(methoxy-poly(ethylene glycol)) with a single N-hydroxysuccinimide ester conjugation handle (Y-(mPEG)2-NHS) is a Y-shaped branched precision PEG derivative. It contains two methoxy-capped PEG arms and a single N-hydroxysuccinimide ester conjugation terminus. Discrete chain lengths with different degrees of polymerization are available. The NHS ester can form amide bonds with primary amines, enabling conjugation to amine-containing small molecules, peptides, proteins, or material surfaces. The two hydrophilic arms attach to a target site through a single functional terminus, allowing arm length, branched topology, and reactive-end chemistry to be studied as separate variables in molecular modification. Applications: Branched PEGylation; Single-site bioconjugation; Two-arm hydrophilic layers and topology studies; Amine modification in proteins and peptides; Amine-functionalized surface conjugation. Customization available.
Y-shapedbis(methoxy-poly(ethylene glycol)) with a single maleimide conjugation handle (Y-(mPEG)2-MAL) is a Y-shaped branched precision PEG derivative. It contains two methoxy-capped PEG arms and a single maleimide conjugation terminus. Discrete chain lengths with different degrees of polymerization are available. The maleimide can add to cysteine thiols or other thiolated modules, providing a handle for conjugation at thiol sites. The two hydrophilic arms attach to a target site through a single functional terminus, allowing arm length, branched topology, and reactive-end chemistry to be studied as separate variables in molecular modification. Applications: Branched PEGylation; Single-site bioconjugation; Two-arm hydrophilic layers and topology studies; Cysteine-site modification; Thiol-selective bioconjugation. Customization available.
4-Armhydroxyl-functionalized discrete poly(ethylene glycol) (4-Arm-PEG-OH) is a 4-arm precision PEG derivative. The PEG arms present terminal hydroxyl groups. Discrete chain lengths with different degrees of polymerization are available. The terminal hydroxyl group can be further modified by esterification, etherification, or other functional-group transformations. The multiarm structure provides attachment sites for multivalent ligand display or network construction. Arm number, chain length, and functional-group equivalents can be varied to compare crosslink spacing and molecular presentation. In this series, n denotes the number of ethylene glycol repeat units in each PEG arm. Applications: Four-arm PEG multivalent conjugation; Branched PEG construction; Crosslinking and site-density studies; Precision PEG derivatization; Bioconjugation linker synthesis. Customization available.
Methoxy-poly(ethyleneglycol)-1,2-Distearoyl-sn-glycero-3-phosphoethanolamine(mPEG-DSPE) is an amphiphilic PEG lipid combining a di-C18 acyl phospholipid anchor with a defined-length hydrophilic PEG segment. Discrete chain lengths with different degrees of polymerization are available. The methoxy cap avoids introducing an additional conventional conjugation site at the hydrophilic chain end, allowing PEG chain length to serve as an independent variable in surface-layer design. It can be used to construct interfaces in membrane-related systems and nanoparticle formulations, enabling comparisons of anchoring structure, hydrophilic chain length, terminal functionality, and formulation dispersion. Applications: Liposome membrane surface modification; Phospholipid hydrophilic-layer construction; Ligand-presentation studies. Customization available.
Methoxy-poly(ethyleneglycol)-1,2-Distearoyl-sn-glycero-3-phosphoethanolamine(mPEG-DSPE) is an amphiphilic PEG lipid combining a di-C18 acyl phospholipid anchor with a defined-length hydrophilic PEG segment. Discrete chain lengths with different degrees of polymerization are available. The methoxy cap avoids introducing an additional conventional conjugation site at the hydrophilic chain end, allowing PEG chain length to serve as an independent variable in surface-layer design. It can be used to construct interfaces in membrane-related systems and nanoparticle formulations, enabling comparisons of anchoring structure, hydrophilic chain length, terminal functionality, and formulation dispersion. Applications: Liposome membrane surface modification; Phospholipid hydrophilic-layer construction; Ligand-presentation studies. Customization available.
Methoxy-poly(ethyleneglycol)-N,N-Ditetradecylacetamide(mPEG-DMA) is an amphiphilic PEG lipid combining a di-C14 alkyl amide anchor with a defined-length hydrophilic PEG segment. Discrete chain lengths with different degrees of polymerization are available. The methoxy cap avoids introducing an additional conventional conjugation site at the hydrophilic chain end, allowing PEG chain length to serve as an independent variable in surface-layer design. It can be used to construct interfaces in membrane-related systems and nanoparticle formulations, enabling comparisons of anchoring structure, hydrophilic chain length, terminal functionality, and formulation dispersion. Applications: Lipid nanoparticle interface design; Amide-linkedlipid-anchor comparisons; Nucleic acid carrier formulation studies. Customization available.
Polysorbate 80 (Tween80) is a nonionic polyoxyethylene surfactant material. It combines a hydrophilic polyoxyethylene component with a hydrophobic oleate component. It can serve as a structural component in interfacial assembly and formulation dispersion. Guest type, oil/water composition, and surfactant loading can be varied to compare solubilization, emulsification, and dispersion, helping select an interfacial composition appropriate to the target formulation. Applications: Solubilization-system screening; Nonionic emulsifying formulations; Dispersion systems and oil/water interface studies. Customization available.
Methoxy-poly(ethyleneglycol)-block-Poly(D,L-lactic acid) (mPEG-b-PDLLA_n) is a block material that covalently combines a defined-length PEG segment with a polyester structure derived from D/L-lactic acid. Discrete chain lengths with different degrees of polymerization are available. Different segment compositions provide a structural basis for comparing hydrophilic–hydrophobic balance, side-chain presentation, or hydrophilic backbones. The methoxy end group defines the direction of chain-end capping or further conjugation. Solution conditions and target guests can be varied to compare dispersion, assembly, and subsequent functionalization. Applications: Methoxy-capped block materials; Block-segment ratio studies; Polyester assembly; Hydrophobic-guest compatibility; Hydrolysis and stereochemical-composition studies. Customization available.
Methoxy-poly(ethyleneglycol)-block-Poly(D,L-lactic acid) (mPEG-b-PDLLA_n) is a block material that covalently combines a defined-length PEG segment with a polyester structure derived from D/L-lactic acid. Discrete chain lengths with different degrees of polymerization are available. Different segment compositions provide a structural basis for comparing hydrophilic–hydrophobic balance, side-chain presentation, or hydrophilic backbones. The methoxy end group defines the direction of chain-end capping or further conjugation. Solution conditions and target guests can be varied to compare dispersion, assembly, and subsequent functionalization. Applications: Methoxy-capped block materials; Block-segment ratio studies; Polyester assembly; Hydrophobic-guest compatibility; Hydrolysis and stereochemical-composition studies. Customization available.
Methoxy-poly(ethyleneglycol)-block-Poly(epsilon-caprolactone)(mPEG-b-PCL_n) is a block material that covalently combines a defined-length PEG segment with a caprolactone-derived polyester segment. Discrete chain lengths with different degrees of polymerization are available. Different segment compositions provide a structural basis for comparing hydrophilic–hydrophobic balance, side-chain presentation, or hydrophilic backbones. The methoxy end group defines the direction of chain-end capping or further conjugation. Solution conditions and target guests can be varied to compare dispersion, assembly, and subsequent functionalization. Applications: Methoxy-capped block materials; Block-segment ratio studies; Hydrophobic-guest encapsulation studies; Amphiphilic material assembly; Polyester compatibility. Customization available.
Methoxy-poly(ethyleneglycol)-block-Polysarcosine(mPEG-b-PSar_n) is a block material that covalently combines a defined-length PEG segment with an N-methylated peptoid backbone. Discrete chain lengths with different degrees of polymerization are available. Different segment compositions provide a structural basis for comparing hydrophilic–hydrophobic balance, side-chain presentation, or hydrophilic backbones. The methoxy end group defines the direction of chain-end capping or further conjugation. Solution conditions and target guests can be varied to compare dispersion, assembly, and subsequent functionalization. Applications: Methoxy-capped block materials; Block-segment ratio studies; Hydrophilic segments as alternatives to PEG; Peptoid material conjugation; Hydrophilic surface-layer construction. Customization available.
1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-conjugatedPoly(oligo(ethylene glycol) methyl ether methacrylate) (DSPE-POEGMA) is an amphiphilic material that covalently combines a di-C18 acyl phospholipid anchor with a hydrophilic polymer of defined degree of polymerization. Discrete chain lengths with different degrees of polymerization are available. Oligo(ethylene glycol) comb side chains form the hydrophilic component. Comparisons with PEG materials bearing the same lipid anchor allow repeat-unit chemistry and hydrophobic anchoring structure to be studied as separate formulation variables. Applications: Alternative polymer–lipid screening; Comb-likehydrophilic-layer construction; Side-chain presentation studies; Comparisons of alternatives to linear PEG; Liposome membrane surface modification. Customization available.
Polyglycerol (PG) is a functional polymer with a defined degree of polymerization. It incorporates a glycerol-derivedoxygen-containing backbone. Discrete chain lengths with different degrees of polymerization are available. Repeat-unit composition and side-chain structure provide material-design variables distinct from linear PEG, enabling comparisons with homologous materials of different chain lengths or backbones. It supports functionalization and material-structure studies organized around segment length, actually available attachment sites, and interfacial presentation. Applications: Oxygen-containing segment design; Hydrophilic-material conjugation; Glycerol-derived backbone studies. Customization available.
Poly(D,L-lactic acid) (PDLLA) is a functional polymer with a defined degree of polymerization. It incorporates a polyester structure derived from D/L-lactic acid. Discrete chain lengths with different degrees of polymerization are available. Repeat-unit composition and side-chain structure provide material-design variables distinct from linear PEG, enabling comparisons with homologous materials of different chain lengths or backbones. It supports functionalization and material-structure studies organized around segment length, actually available attachment sites, and interfacial presentation. Applications: Polyester assembly; Hydrophobic-guest compatibility; Hydrolysis and stereochemical-composition studies. Customization available.
1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-conjugatedPoly(oligo(ethylene glycol) methyl ether methacrylate) (DSPE-POEGMA) is an amphiphilic material that covalently combines a di-C18 acyl phospholipid anchor with a hydrophilic polymer of defined degree of polymerization. Discrete chain lengths with different degrees of polymerization are available. Oligo(ethylene glycol) comb side chains form the hydrophilic component. Comparisons with PEG materials bearing the same lipid anchor allow repeat-unit chemistry and hydrophobic anchoring structure to be studied as separate formulation variables. Applications: Alternative polymer–lipid screening; Comb-likehydrophilic-layer construction; Side-chain presentation studies; Comparisons of alternatives to linear PEG; Liposome membrane surface modification. Customization available.
Cyanine 7-poly(ethyleneglycol)-N-hydroxysuccinimide ester (Cy7-PEG-NHS) is a functional dye combining a Cy7 cyanine chromophore, a defined-length PEG spacer, and an N-hydroxysuccinimide ester conjugation terminus. The PEG spacer is available in discrete chain lengths with different degrees of polymerization. The NHS ester can form amide bonds with primary amines, enabling conjugation to amine-containing small molecules, peptides, proteins, or material surfaces. The PEG spacer separates the chromophore from the target attachment site. Chain length can be selected in relation to labeling position, local environment, and conjugate dispersion. Applications: Fluorescent labeling and tracing; Cy7 cyanine-probe construction; Amine modification in proteins and peptides; Amine-functionalized surface conjugation. Customization available.
Fluorescein-poly(ethyleneglycol)-N-hydroxysuccinimide ester (Fluorescein-PEG-NHS) is a functional dye combining a fluorescein chromophore, a defined-length PEG spacer, and an N-hydroxysuccinimide ester conjugation terminus. The PEG spacer is available in discrete chain lengths with different degrees of polymerization. The NHS ester can form amide bonds with primary amines, enabling conjugation to amine-containing small molecules, peptides, proteins, or material surfaces. The PEG spacer separates the chromophore from the target attachment site. Chain length can be selected in relation to labeling position, local environment, and conjugate dispersion. Applications: Fluorescent labeling and tracing; Fluorescein-probe construction; Amine modification in proteins and peptides; Amine-functionalized surface conjugation. Customization available.
Cyanine 7-poly(ethyleneglycol)-N-hydroxysuccinimide ester (Cy7-PEG-NHS) is a functional dye combining a Cy7 cyanine chromophore, a defined-length PEG spacer, and an N-hydroxysuccinimide ester conjugation terminus. The PEG spacer is available in discrete chain lengths with different degrees of polymerization. The NHS ester can form amide bonds with primary amines, enabling conjugation to amine-containing small molecules, peptides, proteins, or material surfaces. The PEG spacer separates the chromophore from the target attachment site. Chain length can be selected in relation to labeling position, local environment, and conjugate dispersion. Applications: Fluorescent labeling and tracing; Cy7 cyanine-probe construction; Amine modification in proteins and peptides; Amine-functionalized surface conjugation. Customization available.
Cyanine 7-poly(ethyleneglycol)-maleimide(Cy7-PEG-MAL) is a functional dye combining a Cy7 cyanine chromophore, a defined-length PEG spacer, and a maleimide conjugation terminus. The PEG spacer is available in discrete chain lengths with different degrees of polymerization. The maleimide can add to cysteine thiols or other thiolated modules, providing a handle for conjugation at thiol sites. The PEG spacer separates the chromophore from the target attachment site. Chain length can be selected in relation to labeling position, local environment, and conjugate dispersion. Applications: Fluorescent labeling and tracing; Cy7 cyanine-probe construction; Cysteine-site modification; Thiol-selective bioconjugation. Customization available.
Alpha-(terminalalkyne)-omega-(hydroxy)poly(ethylene glycol) (Alkyne-PEG-OH) is a heterobifunctional precision PEG derivative with a defined chain length. The two ends bear terminal alkyne and hydroxyl groups, respectively. Discrete chain lengths with different degrees of polymerization are available. The terminal alkyne can undergo suitable copper-catalyzed cycloaddition with azides, linking the PEG spacer to target molecular modules. The terminal hydroxyl group can be further modified by esterification, etherification, or other functional-group transformations. The two end groups can be coupled sequentially using compatible reactions and appropriate protection strategies, enabling surface immobilization, functional-molecule bridging, and directional spacer synthesis. Applications: Copper-catalyzedazide–alkyne click chemistry; Probe and ligand assembly; Alkyne-linker synthesis; Precision PEG derivatization; Bioconjugation linker synthesis; Drug modification and functional-molecule conjugation. Customization available.
Azido-PEG4-Amine(H2N-PEG-N3) is a heterobifunctional precision PEG derivative with a defined chain length. The two ends bear azide and primary amine groups, respectively. Discrete chain lengths with different degrees of polymerization are available. The azide supports conjugation through azide–alkyne click chemistry. The terminal amine can be further modified through amidation or other functional-group transformations, enabling bioconjugation, drug modification, and synthesis of functional PEG derivatives and precision molecular linkers. Applications: Click chemistry; Bioconjugation; Drug modification; Precision PEG derivatization; Bifunctional molecular linker synthesis. Customization available.
Alpha-(dibenzocyclooctyne)-omega-(N-hydroxysuccinimide ester) poly(ethylene glycol) (DBCO-PEG-NHS) is a heterobifunctional precision PEG derivative with a defined chain length. The two ends bear dibenzocyclooctyne (DBCO) and N-hydroxysuccinimide ester groups, respectively. Discrete chain lengths with different degrees of polymerization are available. The strained DBCO alkyne can undergo copper-free click reactions with azides, enabling attachment to molecules or materials with preinstalled azide sites. The NHS ester can form amide bonds with primary amines, enabling conjugation to amine-containing small molecules, peptides, proteins, or material surfaces. The two end groups can be coupled sequentially using compatible reactions and appropriate protection strategies, enabling surface immobilization, functional-molecule bridging, and directional spacer synthesis. Applications: Copper-free click chemistry; Azide-bearing biomolecule labeling; Bioorthogonal linkers; Amine modification in proteins and peptides; Amine-functionalized surface conjugation; Activated-ester linker synthesis. Customization available.
Alpha-(terminalalkyne)-omega-(hydroxy)poly(ethylene glycol) (Alkyne-PEG-OH) is a heterobifunctional precision PEG derivative with a defined chain length. The two ends bear terminal alkyne and hydroxyl groups, respectively. Discrete chain lengths with different degrees of polymerization are available. The terminal alkyne can undergo suitable copper-catalyzed cycloaddition with azides, linking the PEG spacer to target molecular modules. The terminal hydroxyl group can be further modified by esterification, etherification, or other functional-group transformations. The two end groups can be coupled sequentially using compatible reactions and appropriate protection strategies, enabling surface immobilization, functional-molecule bridging, and directional spacer synthesis. Applications: Copper-catalyzedazide–alkyne click chemistry; Probe and ligand assembly; Alkyne-linker synthesis; Precision PEG derivatization; Bioconjugation linker synthesis; Drug modification and functional-molecule conjugation. Customization available.
Primary amine-functionalized discrete poly(ethyleneglycol)-valyl-citrulline-p-aminobenzyl alcohol (H2N-PEG-Val-Cit-PAB-OH) is an ADC linker intermediate containing a defined-length PEG spacer. It contains a primary amine reactive terminus and a valine–citrulline dipeptide. Discrete chain lengths with different degrees of polymerization are available. The primary amine can react with activated carboxyl groups or NHS esters to form amide bonds and introduce carboxyl-containing functional moieties. The valine–citrulline dipeptide provides a sequence variable for studies of protease-cleavable linkers. The PAB spacer links peptide cleavage to the subsequent self-immolation process. The PAB hydroxyl group retains a synthetic handle for subsequent activation and payload derivatization. Applications: ADC linker and payload-precursor synthesis; Valine–citrulline dipeptide cleavage studies; Modular antibody conjugation; Amide-based bioconjugation. Customization available.
Maleimide-functionalized discrete poly(ethyleneglycol)-valyl-citrulline-p-aminobenzyl alcohol (MAL-PEG-Val-Cit-PAB-OH) is an ADC linker intermediate containing a defined-length PEG spacer. It contains a maleimide reactive terminus and a valine–citrulline dipeptide. Discrete chain lengths with different degrees of polymerization are available. The maleimide can add to cysteine thiols or other thiolated modules, providing a handle for conjugation at thiol sites. The valine–citrulline dipeptide provides a sequence variable for studies of protease-cleavable linkers. The PAB spacer links peptide cleavage to the subsequent self-immolation process. The PAB hydroxyl group retains a synthetic handle for subsequent activation and payload derivatization. Applications: ADC linker and payload-precursor synthesis; Valine–citrulline dipeptide cleavage studies; Modular antibody conjugation; Cysteine-site modification. Customization available.
Primary amine-functionalized discrete poly(ethyleneglycol)-valyl-citrulline-p-aminobenzyl alcohol (H2N-PEG-Val-Cit-PAB-OH) is an ADC linker intermediate containing a defined-length PEG spacer. It contains a primary amine reactive terminus and a valine–citrulline dipeptide. Discrete chain lengths with different degrees of polymerization are available. The primary amine can react with activated carboxyl groups or NHS esters to form amide bonds and introduce carboxyl-containing functional moieties. The valine–citrulline dipeptide provides a sequence variable for studies of protease-cleavable linkers. The PAB spacer links peptide cleavage to the subsequent self-immolation process. The PAB hydroxyl group retains a synthetic handle for subsequent activation and payload derivatization. Applications: ADC linker and payload-precursor synthesis; Valine–citrulline dipeptide cleavage studies; Modular antibody conjugation; Amide-based bioconjugation. Customization available.
Terminal alkyne-functionalized discrete poly(ethyleneglycol)-valyl-citrulline-p-aminobenzyl alcohol (Alkyne-PEG-Val-Cit-PAB-OH) is an ADC linker intermediate containing a defined-length PEG spacer. It contains a terminal alkyne reactive terminus and a valine–citrulline dipeptide. Discrete chain lengths with different degrees of polymerization are available. The terminal alkyne can undergo suitable copper-catalyzed cycloaddition with azides, linking the PEG spacer to target molecular modules. The valine–citrulline dipeptide provides a sequence variable for studies of protease-cleavable linkers. The PAB spacer links peptide cleavage to the subsequent self-immolation process. The PAB hydroxyl group retains a synthetic handle for subsequent activation and payload derivatization. Applications: ADC linker and payload-precursor synthesis; Valine–citrulline dipeptide cleavage studies; Modular antibody conjugation; Copper-catalyzedazide–alkyne click chemistry. Customization available.
Need a precision polymer with a specific degree of polymerization, end groups, or block structure? Once you submit your request, we evaluate the synthesis plan before proceeding with synthesis, quality control, and delivery.
4Quality ControlStructural characterization and testing
5DeliveryShipped after results are confirmed
Technology Platform& Strengths
Our capabilities span molecular design, precision synthesis, structural characterization, functional evaluation, and scale-up manufacturing. We support applications in pharmaceutical excipients, nanomedicine, nucleic acid delivery, high-performance resins, and high-end electronic chemicals.
Core Capabilities
Molecular Design
Precision Synthesis
Structural Characterization
Functional Evaluation
Scale-Up Manufacturing
Emerging Directions
Biodegradable polyesters, including poly(lactic-co-glycolic acid) (PLGA), as well as polypeptides
DUV and EUV Photoresist Resins
Carbon Fiber Precursors
Self-Healing Coatings
Other Key Functional Polymer Materials
Applications
Pharmaceutical Excipients
Nanomedicines
Nucleic Acid Delivery
High-Performance Resins
High-End Electronic Chemicals
Well-Defined Structure
Precise Chain Length
Consistent Quality
AI and Automation Platform for Polymer R&D
Our platform combines automated synthesis, online spectroscopic and chromatographic analysis, high-throughput experimentation, reaction kinetics modeling, and machine learning. Its closed-loop workflow cycles through automated experiments, real-time analysis, model training, formulation and process optimization, and experimental validation. This supports polymerization parameter prediction, copolymer sequence design, and the inverse design of materials for target properties.
Patents for which the company was granted rights through research commercialization, along with related pending patent applications and granted patents.
