mPEG-OMs

Methoxy-poly(ethylene glycol)-methanesulfonate (mPEG-OMs) is a monofunctional precision PEG derivative with a defined chain length. One end bears a methoxy group. The other end bears a mesylate group. Discrete chain lengths with different degrees of polymerization are available. The mesylate provides a handle for nucleophilic substitution, allowing chain-segment construction and installation of the final functional terminus to be performed separately. Capping one end defines the direction of derivatization, enabling the hydrophilic PEG segment to be attached to a target molecule and functional linkers of the required length to be constructed.

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