mPEG-CH2COOH

Methoxy-poly(ethylene glycol)-carboxymethyl (mPEG-CH2COOH) is a monofunctional precision PEG derivative with a defined chain length. One end bears a methoxy group. The other end bears a carboxymethyl group. Discrete chain lengths with different degrees of polymerization are available. The carboxymethyl group can be activated for coupling with primary amines. Its single methylene group defines the local connection between the reactive carboxyl group and the polyether chain. Capping one end defines the direction of derivatization, enabling the hydrophilic PEG segment to be attached to a target molecule and functional linkers of the required length to be constructed.

Customization available.