mPEG-DBCO

Methoxy-poly(ethylene glycol)-dibenzocyclooctyne (mPEG-DBCO) is a monofunctional precision PEG derivative with a defined chain length. One end bears a methoxy group. The other end bears a dibenzocyclooctyne (DBCO) group. Discrete chain lengths with different degrees of polymerization are available. The strained DBCO alkyne can undergo copper-free click reactions with azides, enabling attachment to molecules or materials with preinstalled azide sites. Capping one end defines the direction of derivatization, enabling the hydrophilic PEG segment to be attached to a target molecule and functional linkers of the required length to be constructed.

Customization available.