mPEG-BCN

Methoxy-poly(ethylene glycol)-bicyclononyne (mPEG-BCN) is a monofunctional precision PEG derivative with a defined chain length. One end bears a methoxy group. The other end bears a bicyclononyne (BCN) group. Discrete chain lengths with different degrees of polymerization are available. BCN is a strained alkyne that can undergo copper-free cycloaddition with azides, allowing comparisons of different strained-alkyne conjugation termini. Capping one end defines the direction of derivatization, enabling the hydrophilic PEG segment to be attached to a target molecule and functional linkers of the required length to be constructed.

Customization available.