mPEG-SPDP

Methoxy-poly(ethylene glycol)-pyridyl disulfide (mPEG-SPDP) is a monofunctional precision PEG derivative with a defined chain length. One end bears a methoxy group. The other end bears a pyridyl disulfide group. Discrete chain lengths with different degrees of polymerization are available. The pyridyl disulfide can exchange with thiols to form disulfide linkages, providing reducible molecular connection sites. Capping one end defines the direction of derivatization, enabling the hydrophilic PEG segment to be attached to a target molecule and functional linkers of the required length to be constructed.

Customization available.