HO-PEG-Allyl

Alpha-(hydroxy)-omega-(allyl ether) poly(ethylene glycol) (HO-PEG-Allyl) is a heterobifunctional precision PEG derivative with a defined chain length. The two ends bear hydroxyl and allyl ether groups, respectively. Discrete chain lengths with different degrees of polymerization are available. The terminal hydroxyl group can be further modified by esterification, etherification, or other functional-group transformations. The allyl group can participate in thiol–ene reactions or suitable alkene transformations, providing a conjugation handle for thiol-containing modules. The two end groups can be coupled sequentially using compatible reactions and appropriate protection strategies, enabling surface immobilization, functional-molecule bridging, and directional spacer synthesis.

Customization available.