HS-PEG-NHFmoc

Alpha-(sulfanyl)-omega-(fluorenylmethoxycarbonyl-protected amino) poly(ethylene glycol) (HS-PEG-FmocNH) is a heterobifunctional precision PEG derivative with a defined chain length. The two ends bear thiol and Fmoc-protected amine groups, respectively. Discrete chain lengths with different degrees of polymerization are available. The thiol can add to maleimides or participate in disulfide formation, offering different molecular conjugation routes. Fmoc protection facilitates sequential conjugation. Amine coupling can follow deprotection under conditions compatible with the target system. The two end groups can be coupled sequentially using compatible reactions and appropriate protection strategies, enabling surface immobilization, functional-molecule bridging, and directional spacer synthesis.

Customization available.