BocNH-PEG-ONH2

Alpha-(tert-butoxycarbonyl-protected amino)-omega-(aminooxy) poly(ethylene glycol) (BocNH-PEG-ONH2) is a heterobifunctional precision PEG derivative with a defined chain length. The two ends bear Boc-protected amine and aminooxy groups, respectively. Discrete chain lengths with different degrees of polymerization are available. Boc protection separates amine reactions from other synthetic steps. Appropriate deprotection exposes a primary amine for subsequent conjugation. The aminooxy group can condense with aldehydes or ketones to form oxime bonds, providing a conjugation route for carbonyl-containing molecules and carriers. The two end groups can be coupled sequentially using compatible reactions and appropriate protection strategies, enabling surface immobilization, functional-molecule bridging, and directional spacer synthesis.

Customization available.