CH2COOMe-PEG-CH2COOMe

Alpha,omega-bis(methyl-protected carboxymethyl) poly(ethylene glycol) (MeOOCCH2-PEG-CH2COOMe) is a homobifunctional precision PEG derivative with a defined chain length. Both ends bear methyl-ester-protected carboxymethyl groups. Discrete chain lengths with different degrees of polymerization are available. The methyl ester remains available for subsequent ester transformations, allowing a conjugatable carboxyl group to be introduced after other linking steps. Identical reactive sites at both ends support molecular bridging or derivatization on both sides. The conjugation scheme can be designed around the number of target sites.

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