3-Arm-PEG-DBCO

3-Arm dibenzocyclooctyne-functionalized discrete poly(ethylene glycol) (3-Arm-PEG-DBCO) is a 3-arm precision PEG derivative. The PEG arms present terminal dibenzocyclooctyne (DBCO) groups. Discrete chain lengths with different degrees of polymerization are available. The strained DBCO alkyne can undergo copper-free click reactions with azides, enabling attachment to molecules or materials with preinstalled azide sites. The multiarm structure provides attachment sites for multivalent ligand display or network construction. Arm number, chain length, and functional-group equivalents can be varied to compare crosslink spacing and molecular presentation. In this series, n denotes the number of ethylene glycol repeat units in each PEG arm.

Customization available.