SPDP-PEG-DPPE

Pyridyl disulfide-poly(ethylene glycol)-1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine (SPDP-PEG-DPPE) is an amphiphilic PEG lipid combining a di-C16 acyl phospholipid anchor with a defined-length hydrophilic PEG segment. Discrete chain lengths with different degrees of polymerization are available. The pyridyl disulfide can exchange with thiols to form disulfide linkages, providing reducible molecular connection sites. It can be used to construct interfaces in membrane-related systems and nanoparticle formulations, enabling comparisons of anchoring structure, hydrophilic chain length, terminal functionality, and formulation dispersion.

Customization available.