Alkyne-PEG-DSPE

Terminal alkyne-poly(ethylene glycol)-1,2-Distearoyl-sn-glycero-3-phosphoethanolamine (Alkyne-PEG-DSPE) is an amphiphilic PEG lipid combining a di-C18 acyl phospholipid anchor with a defined-length hydrophilic PEG segment. Discrete chain lengths with different degrees of polymerization are available. The terminal alkyne can undergo suitable copper-catalyzed cycloaddition with azides, linking the PEG spacer to target molecular modules. It can be used to construct interfaces in membrane-related systems and nanoparticle formulations, enabling comparisons of anchoring structure, hydrophilic chain length, terminal functionality, and formulation dispersion.

Customization available.