Alkyne-PEG-DMA

Terminal alkyne-poly(ethylene glycol)-N,N-Ditetradecylacetamide (Alkyne-PEG-DMA) is an amphiphilic PEG lipid combining a di-C14 alkyl amide anchor with a defined-length hydrophilic PEG segment. Discrete chain lengths with different degrees of polymerization are available. The terminal alkyne can undergo suitable copper-catalyzed cycloaddition with azides, linking the PEG spacer to target molecular modules. It can be used to construct interfaces in membrane-related systems and nanoparticle formulations, enabling comparisons of anchoring structure, hydrophilic chain length, terminal functionality, and formulation dispersion.

Customization available.