PRODUCT SERIES

TCO-PEG-DMA

Trans-cyclooctene-poly(ethylene glycol)-N,N-Ditetradecylacetamide (TCO-PEG-DMA) is an amphiphilic PEG lipid combining a di-C14 alkyl amide anchor with a defined-length hydrophilic PEG segment. Discrete chain lengths with different degrees of polymerization are available. Trans-cyclooctene can pair with tetrazines in inverse-electron-demand Diels–Alder reactions for assembly of bioorthogonal modules. It can be used to construct interfaces in membrane-related systems and nanoparticle formulations, enabling comparisons of anchoring structure, hydrophilic chain length, terminal functionality, and formulation dispersion.

Applications:

  • Lipid nanoparticle interface design;
  • Amide-linked lipid-anchor comparisons;
  • Nucleic acid carrier formulation studies;
  • Tetrazine-paired bioorthogonal ligation;
  • Rapid probe assembly studies.

Customization available.

30 Catalog Nos. · Choose a pack size to add it to your inquiry list

Catalog No. / Product NameDegree of Polymerization (n)Exact MassPack Size & Inquiry
PPT-490-004
TCO-PEG4-DMA
4794.67
PPT-490-005
TCO-PEG5-DMA
5838.70
PPT-490-006
TCO-PEG6-DMA
6882.73
PPT-490-007
TCO-PEG7-DMA
7926.75
PPT-490-008
TCO-PEG8-DMA
8970.78
PPT-490-009
TCO-PEG9-DMA
91014.81
PPT-490-010
TCO-PEG10-DMA
101058.83
PPT-490-011
TCO-PEG11-DMA
111102.86
PPT-490-012
TCO-PEG12-DMA
121146.88
PPT-490-013
TCO-PEG13-DMA
131190.91
PPT-490-014
TCO-PEG14-DMA
141234.94
PPT-490-015
TCO-PEG15-DMA
151278.96
PPT-490-016
TCO-PEG16-DMA
161322.99
PPT-490-017
TCO-PEG17-DMA
171367.02
PPT-490-018
TCO-PEG18-DMA
181411.04
PPT-490-019
TCO-PEG19-DMA
191455.07
PPT-490-020
TCO-PEG20-DMA
201499.09
PPT-490-021
TCO-PEG21-DMA
211543.12
PPT-490-022
TCO-PEG22-DMA
221587.15
PPT-490-023
TCO-PEG23-DMA
231631.17
PPT-490-024
TCO-PEG24-DMA
241675.20
PPT-490-028
TCO-PEG28-DMA
281852.31
PPT-490-032
TCO-PEG32-DMA
322028.41
PPT-490-036
TCO-PEG36-DMA
362204.52
PPT-490-045
TCO-PEG45-DMA
452600.75
PPT-490-048
TCO-PEG48-DMA
482732.83
PPT-490-064
TCO-PEG64-DMA
643437.25
PPT-490-096
TCO-PEG96-DMA
964847.09
PPT-490-112
TCO-PEG112-DMA
1125551.51
PPT-490-192
TCO-PEG192-DMA
1929075.62

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