Phosphonate-PEG-DMG

Phosphonic acid-poly(ethylene glycol)-Dimyristoylglycerol (Phosphonate-PEG-DMG) is an amphiphilic PEG lipid combining a dimyristoylglycerol anchor with a defined-length hydrophilic PEG segment. Discrete chain lengths with different degrees of polymerization are available. The phosphonic acid terminus supports coordination and surface-interaction studies, enabling comparisons of phosphonic acid and phosphate-ester terminal chemistries. It can be used to construct interfaces in membrane-related systems and nanoparticle formulations, enabling comparisons of anchoring structure, hydrophilic chain length, terminal functionality, and formulation dispersion.

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