mPEG-b-PDab (NB)_m

Methoxy-poly(ethylene glycol)-block-Poly(L-2,4-diaminobutyric acid) with o-nitrobenzyloxycarbonyl-protected side-chain amines (mPEG-b-PDab (NB)) is a block material that covalently combines a defined-length PEG segment with a side-chain-protected polypeptide structure. Discrete chain lengths with different degrees of polymerization are available. The o-nitrobenzyloxycarbonyl protection allows side-chain amine transformations and attachment of other segments to be performed sequentially, supporting assembly of protected polypeptides and subsequent deprotection studies. The methoxy end group defines the direction of chain-end capping or further conjugation. Solution conditions and target guests can be varied to compare dispersion, assembly, and subsequent functionalization.

Customization available.